Research Lines
By combining viral vector-driven protein expression, in vitro and in vivo optogenetics, in vitro and in vivo electrophysiology, calcium imaging, conventional immunostaining, confocal and electronic microscopy, we study different murine models of multiple sclerosis (MS) aiming to understand:
– The role of astrocytes on remyelination
– Glia-glia and neuron-glia communication in MS
– Mechanisms of neuroinflammation
– Axon-oligodendroglia communication features
Funding
FONDECYT Regular, Research Grant #1210940 (2021-2024)
ANID, ECOS-Sud, Research Grant #180013 (2019-2022)
NeurATRIS, EU, Research Grant ANR-11-INBS-0011 (2018-2021)
FONDECYT Iniciación, Research Grant #11160616 (2017-2019)
Collaborations
Dr. María Cecilia Angulo, Inserm U 894 Centre de Psychiatrie et Neurosciences, Paris, France.
Dr. Carole Escartin, UMR 9199, CNRS, CEA, University Paris-Saclay, MIRCen, Fontenay-aux-roses, France.
Dr. Etienne Audinat, Institut de Génomique Fonctionnelle, Department of Neuroscience, University of Montpellier, Montpellier, France.
Dr. Francisco Rivera, Facultad de Medicina, Universidad Austral de Chile, Valdivia, Chile.
Dr. Rodrigo del Río, Facultad de Ciencias Biológicas, P. Universidad Católica de Chile, Santiago, Chile.
Dr. Juan Andrés Orellana, Facultad de Medicina, P. Universidad Catolica de Chile, Santiago, Chile.
Dr. Carlos Puebla, Instituto de Ciencias de la Salud, Universidad de O’Higgins, Rancagua, Chile.
Myelin Lab 